World Class Bodybuilding   Forum

BulkSupplements Egg Whites International A1Supplements.com i-Supplements Strength.com VitaSprings Myprotein Beyondsupplements
Go Back   World Class Bodybuilding Forum > WorldClass RSS Feeds > Peptides RSS FFEDS




Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 01-22-2020, 06:00 PM
Bodybuilding Peptides's Avatar
Bodybuilding Peptides Bodybuilding Peptides Is Off Line
Sponsor

 
Join Date: Feb 2009
Posts: 6,276
Thanks: 1
Thanked 32 Times in 23 Posts
Rep Power: 214
Bodybuilding Peptides is a splendid one to beholdBodybuilding Peptides is a splendid one to beholdBodybuilding Peptides is a splendid one to beholdBodybuilding Peptides is a splendid one to beholdBodybuilding Peptides is a splendid one to beholdBodybuilding Peptides is a splendid one to beholdBodybuilding Peptides is a splendid one to beholdBodybuilding Peptides is a splendid one to beholdBodybuilding Peptides is a splendid one to beholdBodybuilding Peptides is a splendid one to beholdBodybuilding Peptides is a splendid one to behold
rss IGF - Shifting equilibriums in Alzheimer's disease: the complex roles of microglia in

Related Articles Shifting equilibriums in Alzheimer's disease: the complex roles of microglia in neuroinflammation, neuronal survival and neurogenesis.

Neural Regen Res. 2020 Jul;15(7):1208-1219

Authors: Gray SC, Kinghorn KJ, Woodling NS

Abstract
Alzheimer's disease is the leading cause of dementia. Its increased prevalence in developed countries, due to the sharp rise in ageing populations, presents one of the costliest challenges to modern medicine. In order to find disease-modifying therapies to confront this challenge, a more complete understanding of the pathogenesis of Alzheimer's disease is necessary. Recent studies have revealed increasing evidence for the roles played by microglia, the resident innate immune system cells of the brain. Reflecting the well-established roles of microglia in reacting to pathogens and inflammatory stimuli, there is now a growing literature describing both protective and detrimental effects for individual cytokines and chemokines produced by microglia in Alzheimer's disease. A smaller but increasing number of studies have also addressed the divergent roles played by microglial neurotrophic and neurogenic factors, and how their perturbation may play a key role in the pathogenesis of Alzheimer's disease. Here we review recent findings on the roles played by microglia in neuroinflammation, neuronal survival and neurogenesis in Alzheimer's disease. In each case, landmark studies have provided evidence for the divergent ways in which microglia can either promote neuronal function and survival, or perturb neuronal function, leading to cell death. In many cases, the secreted molecules of microglia can lead to divergent effects depending on the magnitude and context of microglial activation. This suggests that microglial functions must be maintained in a fine equilibrium, in order to support healthy neuronal function, and that the cellular microenvironment in the Alzheimer's disease brain disrupts this fine balance, leading to neurodegeneration. Thus, an understanding of microglial homeostasis, both in health and across the trajectory of the disease state, will improve our understanding of the pathogenic mechanisms underlying Alzheimer's disease, and will hopefully lead to the development of microglial-based therapeutic strategies to restore equilibrium in the Alzheimer's disease brain.


PMID: 31960800 [PubMed]



More...
Insulin like growth factors
IGF-1
Igf-1r3

This has been a World Class Bodybuilding automated thread
__________________
W C B B Affiliates

PowderCity.com <---Best Selling Products
BulkSupplements.com <---Save Money, Buy in BULK
IslandSupplements.com <--- Latest Sale Items
I-supplements.com <--- Vip Special Offers
A1Supplements.com <----Clearance Supplements
HideMyAss Security Proxy<---- Protect your online activity
Home Chemistry Conversions <-- home chemistry needs
Help WCBB by using our AMAZON.com link use for any amazon purchase.
Egg Whites International <---100% Bio-Available Egg White Protein
Liquid egg whites recipes ,-- protein shakes, smoothies, full delicious meals etc.
Egg White Fitness Website <-- Site all about Egg Whites
WorldClassBodyBuilding Teeshirts <-- get your WCBB t-shirts here, first design to latest
Reply With Quote
Get your liquid egg whites here at EGG WHITES INTERNATIONAL

Reply

Bookmarks


Currently Active Users Viewing This Thread: 1 (0 members and 1 guests)
 
Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

Forum Jump


All times are GMT -5. The time now is 03:27 AM.



Copyright ©2000 - 2020, Jelsoft Enterprises Ltd.
follow worldclassbodybuilding at facebook follow worldclassbodybuilding at pinterest follow worldclassbodybuilding at twitter