World Class Bodybuilding   Forum

BulkSupplements Egg Whites International A1Supplements.com i-Supplements HideMyAss
Go Back   World Class Bodybuilding Forum > Anabolic Steroid Discussion > Peptide Profiles

Shoutbox
Loading...





Reply
 
Thread Tools Search this Thread Display Modes
  #1  
Old 06-08-2015, 06:08 AM
basskiller's Avatar
basskiller basskiller Is online now
Administrator

 
Join Date: Jan 2004
Location: Bodybuilding heaven
Posts: 119,923
Thanks: 3,267
Thanked 18,099 Times in 10,475 Posts
Rep Power: 3684
basskiller has a reputation beyond reputebasskiller has a reputation beyond reputebasskiller has a reputation beyond reputebasskiller has a reputation beyond reputebasskiller has a reputation beyond reputebasskiller has a reputation beyond reputebasskiller has a reputation beyond reputebasskiller has a reputation beyond reputebasskiller has a reputation beyond reputebasskiller has a reputation beyond reputebasskiller has a reputation beyond repute
Enhancing Healing with BPC-157

Enhancing Healing with BPC-157
bpc-157

BPC 157 (Body Protection Compound-157) is a pentadecapeptide made up of 15 amino acids. The amino acids sequence in BPC 157 is similar to a portion of the human BPC amino acid sequence. Human BPC is found in the gastric juice.
Experiments have shown that BPC 157 enhances the healing of wounds, including tendons wounds such as transected Achilles tendons of rats. The aim of this study was to investigate the probable mechanism that BPC 157 utilizes to accelerate the healing process in an injured tendon. The study used two group of tendon explants of which one group was cultured in a BPC 157-containing medium while the other group was cultured in a medium lacking BPC 157.

These cultures were thereafter examined for tendon fibroblasts outgrowths. Such outgrowths indicated tendon regeneration. The results revealed that the explants’ outgrowth was significantly accelerated in the culture containing BPC 157 as compared to the culture lacking BPC 157. Also, a MTT assay did show that BPC 157 does not directly affect cellular proliferation in a culture of rat-derived Achilles tendon. However, results also showed that BPC 157 significantly increased the survival of cells under oxidative stress.

Furthermore, the Transwell filter migration assay showed that BPC 157 significantly increased in-vitro fibroblast migration in a dose-dependent fashion. Moreover, BPC 157 accelerated the dispersal of the fibroblasts in culture dishes in a dose-dependent manner.

Additionally, FITC-phalloidin staining was able to demonstrate that BPC 157 induces F-actin formation in fibroblasts. Likewise, Western blot analysis was able to detect the production and activation of paxillin and FAK proteins. The western blot analysis also showed that BPC 157 increases the extent of phosphorylation of paxillin and FAK proteins without affecting the amounts produced.
Thus, it can be concluded that BPC 157 enhances the ex-vivo growth and in-vitro cellular migration of fibroblasts derived from tendon explants. Moreover, BPC 157 also increases the probability of a cell surviving under oxidative stress. These actions of BPC 157 are probably mediated by the activation (through phosphorylation) of the proteinic FAK-paxillin pathway.
__________________

W C B B Sponsors
Species Nutrition
Suppz.com - Supplement Superstore
PrecisionPinz
Superpeptides


W C B B Affiliates
PowderCity.com
BulkSupplements.com
HideMyAss Security Proxy<---- Protect your online activity
Home Chemistry Conversions
Egg Whites International <---100% Bio-Available Egg White Protein


Remember... Any advice given on this board is just an opinion and not to be taken as medical advice. WCBB doesn't advocate or condone use of steroids. Check the laws in your country. WCBB just provides the platform in which to discuss such matters
Reply With Quote
Get your liquid egg whites here at EGG WHITES INTERNATIONAL

  #2  
Old 06-08-2015, 07:44 AM
liftsiron's Avatar
liftsiron liftsiron Is Off Line
Moderator

 
Join Date: Feb 2004
Location: Cimmeria
Posts: 4,855
Thanks: 27
Thanked 1,119 Times in 829 Posts
Rep Power: 766
liftsiron has a reputation beyond reputeliftsiron has a reputation beyond reputeliftsiron has a reputation beyond reputeliftsiron has a reputation beyond reputeliftsiron has a reputation beyond reputeliftsiron has a reputation beyond reputeliftsiron has a reputation beyond reputeliftsiron has a reputation beyond reputeliftsiron has a reputation beyond reputeliftsiron has a reputation beyond reputeliftsiron has a reputation beyond repute
It really seems to work for me!
__________________
ADMIN/OWNER@Peak-Muscle
Reply With Quote
Reply

Bookmarks


Currently Active Users Viewing This Thread: 1 (0 members and 1 guests)
 
Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

Forum Jump


All times are GMT -4. The time now is 03:54 AM.



Copyright ©2000 - 2017, Jelsoft Enterprises Ltd.
follow worldclassbodybuilding at facebook follow worldclassbodybuilding at pinterest follow worldclassbodybuilding at twitter