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Old 06-19-2018, 05:37 AM
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rss High serum concentration of estradiol may be a risk factor of prostate enlargement in

High serum concentration of estradiol may be a risk factor of prostate enlargement in aging male in China.

Aging Male. 2018 Jun 18;:1-6

Authors: Xu D, Wu Y, Shen H, Qian S, Qi J

Abstract
OBJECTIVE: Assess the association between serum sex hormone level and prostate volume in men with benign prostatic hyperplasia (BPH).
MATERIAL AND METHODS: The study involved 239 BPH patients from January 2013 to June 2015 in our hospital. Each patient collected age, medical history, height, weight, body mass index, as well as a full examination of sex hormones, and transrectal ultrasound results.
RESULTS: Estradiol (E2) was significantly associated with prostate volume (r = 0.151, p = .02) and transitional zone volume (r = 0.136, p = .035). The association was more significant after adjusting age and BMI (r = 0.253 and 0.250, p = 160 umol/l than those in the patients with E2 < 160 umol/l. Through logistics regression, E2 (p = .012, OR = 1.004) are the only independent risk factor for prostate volume.
CONCLUSIONS: E2 is significantly associated with prostate volume. High concentrations of E2 may be a risk factor for the large volume of prostate.


PMID: 29912660 [PubMed - as supplied by publisher]



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