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Old 11-12-2016, 09:54 PM
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Question What do we know about gdf 8?

Read this about the myostatin blocker: https://www.ncbi.nlm.nih.gov/pubmed/20173658
However, the dose was 20mg per kg which would make for a pricy cycle.

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Old 04-17-2017, 07:01 AM
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Old 04-17-2017, 07:44 AM
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In general pharmacology there is s general rule that in mice and rats you use about 9 times as much as in humans.
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Old 04-18-2017, 08:54 AM
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In general pharmacology there is s general rule that in mice and rats you use about 9 times as much as in humans.
So if you were conducting a clinical trial on people your dose would be 2.2 mg/kg.
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Old 04-18-2017, 11:04 AM
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In general pharmacology there is s general rule that in mice and rats you use about 9 times as much as in humans.


and this is how we get the meds that dont work and the substances that are carcinogenic at 1000 times what is recommended for human
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Old 04-19-2017, 08:24 PM
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Well, this is why I ask. Guy tells me that a doc out of FL is suppling him with some myostatin blocker for like $100. So, while I may be ignorant I still call bullshit.

It appears I was correct just by using common sense.

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Old 04-20-2017, 07:31 AM
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I did a cursory look at the cost. what I found was about $80 mg and at even 2mg per kg per day?

no way................

i think the dose would be better at 20mcg for a human to start with
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Old 04-20-2017, 09:24 PM
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I did a cursory look at the cost. what I found was about $80 mg and at even 2mg per kg per day?

no way................

i think the dose would be better at 20mcg for a human to start with
Yeah, things don't add up. But, the cost seams a bit prohibitive IMHO.

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Old 04-20-2017, 10:09 PM
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YK11 may inhibit myostatin via increased follistatin production.
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Old 04-21-2017, 08:34 AM
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fwiw, blocking myostatin is the holy f'n grail

it's the reason why some guys eat like pigs, don't work out and look like adonis

i think they have known what it does for 30 years, and thus every ten years some supp company promotes it because new folks will believe anything

not a tremendous amount of research on it because, no real medical ailment to cure, like gh was developed for dwarfism in children and then found out wow it works on this also
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