IGF - [Value of nutritional risk screening in evaluating adverse clinical outcomes in

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Related Articles [Value of nutritional risk screening in evaluating adverse clinical outcomes in children with severe pneumonia].

Zhongguo Dang Dai Er Ke Za Zhi. 2017 Mar;19(3):322-326

Authors: Guo XH, Sun YF, Wang JB, Han SZ, Miao J, Cui M


Abstract
OBJECTIVE: To investigate the nutritional risk in children with severe pneumonia using the Screening Tool for the Assessment of Malnutrition in Paediatrics (STAMP) and the association between nutritional risk and adverse clinical outcomes.
METHODS: According to the STAMP score, 216 children with severe pneumonia were classified into high nutritional risk group (HR group; n=98), moderate nutritional risk group (MR group; n=65), and low nutritional risk group (LR group; n=53). Fasting blood samples were collected to measure the levels of insulin-like growth factor-1 (IGF-1), adiponectin, leptin, non-esterified fatty acid (NEFA), albumin, transferrin, prealbumin, and retinol binding protein (RBP). The adverse clinical outcomes were recorded.
RESULTS: Compared with the MR and LR groups, the HR group had significantly lower serum levels of IGF-1, leptin, adiponectin, prealbumin, and RBP, as well as a significantly higher serum level of NEFA (P